Original title: Glycine in the interstellar medium revisited: Resolving conformational complexity kinetically
Judith Wurmel, John M. Simmie · September 2026
Scientists want to find glycine, a simple amino acid that builds proteins on Earth, in deep space. Space rocks like meteorites, comets, and asteroids carry glycine, but past searches in the interstellar mediumThe gas and dust that fills the space between stars. have failed. Glycine can twist into eight different shapes, known as conformations. This study investigates how glycine flips between these shapes in the dark. At temperatures from 300 K down to 10 K, these shape changes happen through quantum mechanical tunnellingA quantum effect where particles pass through energy barriers they classically could not cross., where molecules pass through energy barriers instead of climbing over them. The researchers computed the rates of these shape shifts to understand which forms appear most often. Using these speeds, they provide recommendations to maximise the chances of finally detecting glycine in space.
Imagine you have a key that can fit into a lock in eight different orientations. Normally, you would need to jiggle it or heat it to change its shape. But in the cold of space, there is no heat to jiggle it. In this paper, the key changes shape on its own through a strange quantum effect, and the researchers calculate how fast each shape change happens, so astronomers know which shape to look for.
Astronomers have searched for glycine in space for decades without success. This work shows that glycine's shape-shifting between eight forms happens via quantum tunnelling even in the cold vacuum of space. Knowing these rates tells scientists which forms to look for and when, increasing the chance of finally detecting this key building block of life.
The abstract does not report a detection of glycine. It only provides theoretical calculations of tunnelling rates under dark conditions. The effect of ultraviolet radiation or other interstellar processes on glycine conformers is not addressed. The recommendations are based on these computed rates and have not yet been tested observationally.
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Glycine in the interstellar medium revisited: Resolving conformational complexity kinetically — Judith Wurmel, John M. Simmie
Abstract licence: CC0
Explanation generated by Synthesis from the abstract — it is not the original paper. This is a preprint, so it hasn't necessarily been peer reviewed.