Original title: Polyglycolic Acid Shield Prevents Repeated Delayed Bleeding After Endoscopic Stricturotomy for Anastomotic Stricture in Crohn's Disease: A Case Report
Hidezumi Kikuchi, Taka Asari, Tetsuya Tatsuta, Kazuhiro Nagane +6 · August 2026
Doctors treated a patient with Crohn's disease who had a narrowed area in the lower gut. They used an endoscope, a thin tube with a camera, to cut open the blockage. The procedure opened the path, but serious bleeding started later. Standard fixes like heated forceps, clips, and special gels only gave temporary relief. The bleeding returned nine times within 17 days. A medicine called infliximab also failed to stop it. To fix this, doctors covered the wounded tissue with polyglycolic acid sheets and fibrin glue. This protective shield sealed the wound, stopped the bleeding from coming back, and allowed the patient to avoid abdominal surgery. Shielding wounds this way may help prevent dangerous bleeding after these endoscopic cuts.
Imagine you cut your finger while slicing vegetables. You put on a bandage, but the cut keeps bleeding through it. You try a stronger bandage, then a special gel, then press harder—still bleeding. Finally, you cover the cut with a thin plastic wrap that sticks to the skin and lets the wound heal underneath without being disturbed. In this paper, the cut is a bleeding spot inside the intestine after a scope procedure, and the plastic wrap is a polyglycolic acid sheet that stopped the bleeding when other methods failed.
People with Crohn's disease often need surgery that leaves a narrow connection in the intestine. Fixing that narrowing with a scope can cause dangerous bleeding that keeps coming back. This case shows that covering the wound with a dissolvable sheet might stop the bleeding when nothing else works, potentially saving patients from another major surgery.
This is a single case report, so the finding may not apply to other patients or situations. The abstract does not describe a controlled study or compare PGA sheets to other treatments in a systematic way. It also does not specify long-term outcomes or whether the sheet caused any side effects.
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Polyglycolic Acid Shield Prevents Repeated Delayed Bleeding After Endoscopic Stricturotomy for Anastomotic Stricture in Crohn's Disease: A Case Report — Hidezumi Kikuchi, Taka Asari, Tetsuya Tatsuta et al. — DEN open — doi:10.1002/deo2.70420
Abstract licence: CC BY
Explanation generated by Synthesis from the abstract — it is not the original paper.