Original title: Endoscopic Injection Sclerotherapy With Pre-deflation Ligation for Prolonged Sclerosant Retention in Esophageal Varices: A Case Report
Noriaki Sugawara, Taro Iwatsubo, Masatoshi Kaizuka, Sayaka Tsuji +6 · September 2026
Swollen veins in the food pipe, called esophageal varices, can cause dangerous bleeding. Doctors often treat them by injecting a medicine that clots the veins, followed by tying them off with small bands. However, letting blood flow back in before tying the band can wash the medicine away and trigger bleeding. To fix this, doctors tested a new timing method. While a tiny balloon stayed blown up inside to press on the vein and trap the clotted medicine, they tied the band over the puncture hole first. They tested this in a 59-year-old man. The procedure succeeded without immediate complications. Seven days later, the veins showed signs of clotting, and scans after two months showed they had completely disappeared.
Imagine trying to patch a leaky garden hose. You have a tube of glue to seal the hole, but the moment you take your finger off the spray, water gushes out and washes the glue away before it can set. In this paper, doctors treat swollen veins in the esophagus by injecting a clotting agent. Normally they stop squeezing the vein before tying it off, and blood flow flushes out the medicine. Here, they keep the vein compressed while tying it, giving the medicine time to work.
For patients with liver disease, swollen veins in the esophagus can burst and cause dangerous bleeding. The standard treatment injects a clotting solution, but blood flow can wash it away before it works. This small tweak—keeping the vein compressed during injection—may make the treatment more reliable and safer.
This is a single case report, so the findings may not apply to all patients. There was no comparison with the standard technique. Outcomes beyond two months are not reported.
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Endoscopic Injection Sclerotherapy With Pre-deflation Ligation for Prolonged Sclerosant Retention in Esophageal Varices: A Case Report — Noriaki Sugawara, Taro Iwatsubo, Masatoshi Kaizuka et al. — DEN open — doi:10.1002/deo2.70410
Abstract licence: CC BY
Explanation generated by Synthesis from the abstract — it is not the original paper.