Original title: Feasibility and Safety Profile of Non-anesthesiologist-administered Propofol During Colorectal Endoscopic Submucosal Dissection: A Single-center Study of 454 Procedures
Yumi Kishi, Mayo Tanabe, Naoyuki Uragami, Daijiro Shiomi +13 · September 2026
Doctors often remove early colon growths using a delicate procedure called endoscopic submucosal dissection. Patients need medicine to keep them calm and still, but specialists called anesthesiologists are not always available to give it. Instead, non-anesthesiologists gave patients a sedative called propofolA fast-acting sedative drug that makes you sleepy during procedures.. Researchers studied how well this worked across different age groups, especially older patients. By keeping patients safely sedated, the medical team completed every single procedure. No patient needed extra emergency care or had to stop early because of the sedation. However, the researchers found that longer procedures increased the risk of complications like a very slow heart rate. Patients aged 75 and older also faced higher risks of low blood oxygen and slow heart rates.
Your elderly parent is staying with a niece who has CPR training but is not a nurse. You know she means well, but you're nervous about what might happen if your parent gets ill and needs medical care she isn't fully qualified to give. In this paper, a doctor who is not an anesthesia specialist administers the sedative for a colon procedure. The worry is the same: can someone with training but not the specialty handle it safely, especially for older patients?
Colorectal ESD is a common procedure, but it usually needs an anesthesiologist to manage sedation. If regular doctors can do it safely, hospitals with limited anesthesiologists can offer it more easily. This study shows it's feasible across all ages, which matters for elderly patients who are often considered higher risk.
This is a single-center retrospective study, so the results may not apply everywhere. It doesn't compare with standard anesthesiologist-administered sedation, and it only covers colorectal ESD, not other procedures.
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Feasibility and Safety Profile of Non-anesthesiologist-administered Propofol During Colorectal Endoscopic Submucosal Dissection: A Single-center Study of 454 Procedures — Yumi Kishi, Mayo Tanabe, Naoyuki Uragami et al. — DEN open — doi:10.1002/deo2.70435
Abstract licence: CC BY
Explanation generated by Synthesis from the abstract — it is not the original paper.