Original title: Treatment Adherence and Health-Related Quality of Life Among Patients with Type 2 Diabetes Mellitus in Rajshahi, Bangladesh: A Cross-Sectional Study
Md. Shahinur Rahaman, Md Rizwanul Karim, Subrata Kumer Sen, A.B.M. Nafiz Intekhab +2 · September 2026
Type 2 diabetes is spreading quickly in Bangladesh, but managing it over a lifetime is difficult. When people struggle to take their medicines as prescribed, their health and daily well-being can drop. Researchers set out to see how closely patients follow their treatments and how the disease affects their overall quality of life. They surveyed hospital patients in Rajshahi about their habits, daily difficulties, and blood sugar. They found that most patients had poor blood sugar control, and over forty percent had low adherence to their treatments. Daily well-being was also heavily impacted: very few patients reported perfect health, while many faced severe problems. Interestingly, how well someone stuck to their medicine did not directly link to their quality of life. Instead, health complications caused by diabetes were the strongest predictor of a lower quality of life, highlighting the need to prevent these serious complications.
Imagine having a condition that needs daily medication. You sometimes forget to take it, or skip a dose. But even if you take it perfectly, you could still suffer from other health problems that affect your daily life. In this paper, researchers found that for diabetes patients, these secondary health problems were the main reason for poor quality of life, not how well they took their medicine.
In Bangladesh, diabetes will affect nearly 22 million adults by 2045. This study shows that most patients already have poor blood sugar control and low medication adherence. It also reveals that complications, not adherence, most strongly predict poor quality of life, so preventing complications should be the priority.
This cross-sectional study cannot establish cause and effect. The sample is limited to two tertiary hospitals in Rajshahi, so findings may not represent all of Bangladesh. Adherence was measured via self-report, which may overestimate true adherence. The non-significant association between adherence and quality of life could be due to the modest sample size (n=205).
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Treatment Adherence and Health-Related Quality of Life Among Patients with Type 2 Diabetes Mellitus in Rajshahi, Bangladesh: A Cross-Sectional Study — Md. Shahinur Rahaman, Md Rizwanul Karim, Subrata Kumer Sen et al. — medRxiv — doi:10.64898/2026.09.09.26362693
Abstract licence: CC BY
Explanation generated by Synthesis from the abstract — it is not the original paper. This is a preprint, so it hasn't necessarily been peer reviewed.