Original title: Advances in Skin Regeneration Using Tissue Engineering
Skin substitutes are materials designed to help wounds heal. They can be made from materials without cells, from a person’s own cells, from donated or animal sources, or from synthetic materials. Each type has benefits and drawbacks. None yet works as a complete replacement for all the layers and functions of skin, and researchers are working toward substitutes that quickly develop a blood supply.
Imagine patching a torn coat with a piece of fabric. The patch can cover the hole, but it may not match the coat’s strength, feel, or fit. In this paper, the patch stands for a skin substitute: it can help cover a wound, but a complete replacement must also work like skin and quickly gain a blood supply.
People with wounds may need skin substitutes to support healing. The review describes different materials and sources used to make them, while pointing out that a complete, fast-vascularizing substitute is still unavailable.
The abstract describes a review of available substitute types and their applications, but gives no specific study results or comparisons between products. It does not establish which materials work best, how well any substitute heals wounds, or when a complete functional substitute will be available.
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Advances in Skin Regeneration Using Tissue Engineering — Komal Vig, Atul A. Chaudhari, Shweta Tripathi et al. — International Journal of Molecular Sciences — doi:10.3390/ijms18040789
Abstract licence: CC BY
Explanation generated by Synthesis from the abstract — it is not the original paper.